Ärzteteam

Increased 30-day mortality in very old ICU patients with COVID-19 compared to patients with respiratory failure without COVID-19. Guidet B, Jung C, Flaatten H, Fjølner J, Artigas A, Pinto BB, Schefold JC, Beil M, Sigal S, van Heerden PV, Szczeklik W, Joannidis M, Oeyen S, Kondili E, Marsh B, Andersen FH, Moreno R, Cecconi M, Leaver S, De Lange DW, Boumendil A; VIP2 and COVIP study groups. 
Intensive Care Med. 2022 Apr; 48 (4): 435-447.

The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study.
Jung C, Flaatten H, Fjølner J, Bruno RR, Wernly B, Artigas A, Bollen Pinto B, Schefold JC, Wolff G, Kelm M, Beil M, Sviri S, van Heerden PV, Szczeklik W, Czuczwar M, Elhadi M, Joannidis M, Oeyen S, Zafeiridis T, Marsh B, Andersen FH, Moreno R, Cecconi M, Leaver S, Boumendil A, De Lange DW, Guidet B; COVIP study group. 
Crit Care. 2021 Apr 19; 25(1): 149.

Extracorporeal life support in COVID-19-related acute respiratory distress syndrome: A EuroELSO international survey. 
Mang S, Kalenka A, Broman LM, Supady A, Swol J, Danziger G, Becker A, Hörsch SI, Mertke T, Kaiser R, Bracht H, Zotzmann V, Seiler F, Bals R, Taccone FS, Moerer O, Lorusso R, Bělohlávek J, Muellenbach RM, Lepper PM; COVEC-Study Group. 
Artif Organs. 2021 May; 45(5): 495-505.

Short-term outcome and characteristics of critical care for nontrauma patients in the emergency department. 
Kreß JS, Rüppel M, Haake H, Vom Dahl J, Bergrath S. 
Anaesthesist. 2022 Jan; 71(1): 30-37.

Impella use in real-world cardiogenic shock patients: Sobering outcomes.
Khaled Q. A. Abdullah, Jana V. Roedler, Juergen vom Dahl, Istvan Szendey, Hendrik Haake, Lars Eckardt, Albert Topf, Bernhard Ohnewein, Peter Jirak, Lukas J. Motloch, Bernhard Wernly, Robert Larbig. 
Plos One 16 (2), February 2021.

Myocardial injury in severe COVID-19 is similar to pneumonias of other origin: results from a multicentre study.
Peter Jirak, Robert Larbig, Zornitsa Shomanova, Elisabeth J. Fröb, Daniel Dankl, Christian Torgersen, Nino Frank, Magdalena Mahringer, Dominyka Butkiene, Hendrik Haake, Helmut J.F. Salzer, Thomas Tschoellitsch, Michael Lichtenauer, Alexander Egle, Bernd Lamprecht, Holger Reinecke, Uta C. Hoppe, Rudin Pistulli, Lukas J. Motloch.
ESC Heart Failure Journal, Volume8, Issue1, February 2021, Pages 37-46.

Characteristics and Unexpected COVID-19 Diagnoses in Resuscitation Room Patients during the COVID-19 Outbreak—A Retrospective Case Series.
Sebastian Bergrath, Olaf Aretz, Hendrik Haake, Adrian Ringelstein, Ingo Greiffendorf, Ullrich Graeven and Jochen Windfuhr.
BioMed Research International August 2020: 1-7.

Evaluation of Myocardial Gene Expression Profiling for Superior Diagnosis of Idiopathic Giant-Cell Myocarditis and Clinical Feasibility in a Large Cohort of Patients with Acute Cardiac Decompensation.
Felicitas Escher, Heiko Pietsch, Ganna Aleshcheva, Philip Wenzel, Friedrich Fruhwald, Christian Stumpf, Dirk Westermann, Johann Bauersachs, Frank Enseleit, Frank Ruschitzka, Herbert Nägele, Karl-Ludwig Laugwitz, Hendrik Haake, Norbert Frey, Johannes Brachmann, Kurt Huber, Rüdiger Christian Braun-Dullaeus, MartinW. Bergmann, Jörg Strotmann, Gerian Grönefeld, Jürgen Krülls-Münch, Ralf Westenfeld, Carsten Skurk, Ulf Landmesser, Burkert Pieske, Ulrich M. Gross, Lars Morawietz and Heinz-Peter Schultheiss.
Journal of Clinical Medicine 9 (9), August 2020: 2689.

Extracorporeal Membrane Oxygenation for Critically Ill Patients with COVID-19–related Acute Respiratory Distress Syndrome: Worth the Effort!
Tobias Wengenmayer, Ralf M. Muellenbach,  Fabio Silvio Taccone, Markus Kredel, Armin Kalenka, Jan Bělohlávek, Tobias Spangenberg, Hendrik Haake, Hendrik Bracht, Onnen Moerer,  Roberto Lorusso and Philipp M. Lepper.
American Journal of Respiratory and Critical Care Medicine 202 (10), August 2020.

International registry on the use of the CytoSorb® adsorber in ICU patients.
S. Friesecke, K. Träger, G. A. Schittek, Z. Molnar, F. Bach, K. Kogelmann, R. Bogdanski, A. Weyland, A. Nierhaus, F. Nestler, D. Olboeter, D. Tomescu, D. Jacob, H. Haake, E. Grigoryev, M. Nitsch, A. Baumann, M. Quintel, M. Schott, J. T. Kielstein, A. Meier-Hellmann, F. Born, U. Schumacher, M. Singer, J. Kellum, F. M. Brunkhorst.
Medizinische Klinik – Intensivmedizin und Notfallmedizin volume 114 (2019): 699–707.

Immediate unselected coronary angiography versus delayed triage in survivors of out-of-hospital cardiac arrest without ST-segment elevation: Design and rationale of the TOMAHAWK trial.
Steffen Desch,  Anne Freund, Tobias Graf, Stephan Fichtlscherer, Hendrik Haake, Michael Preusch, Fabian Hammer, Ibrahim Akin, Martin Christ, Christoph Liebetrau, Carsten Skurk, Stephan Steiner, Ingo Voigt, Roland Schmitz, Harald Mudra, Jakob Ledwoch, Niels Menck, Jan Horstkotte, Klaus Pels, Anna Lahmann, Sylvia Otto, Karsten Lenk, Marc-Alexander Ohlow, Christian Hassager, Peter Nordbeck, Uwe Zeymer, Alexander Jobs, Suzanne de Waha-Thiele, Denise Olbrich, Inke König , Kathrin Klinge, Holger Thiele.
American Heart Journal 209, December 2018.

Weaning from prolonged veno-venous extracorporeal membrane oxygenation (ECMO) after transfer to a specialized center: a retrospective study. Frederik Seiler, Franziska C. Trudzinski, Sabrina I. Hörsch, Annegret Kamp, Carlos Metz, Monika Flaig, Mohammad Alqudrah, Holger Wehrfritz, Markus Kredel, Ralf M. Muellenbach, Hendrik Haake, Robert Bals & Philipp M. Lepper.
Journal of Artificial Organs volume 21 (2018): 300–307.

Percutaneous Mechanical Circulation Support Combined with Extracorporeal Membrane Oxygenation (oxyRVAD) in Secondary Right Heart Failure. Lepper, Philipp M.; Hörsch, Sabrina I.; Seiler, Frederik; Kamp, Annegret; Becker, Sören L.; Lensch, Christian; Conzelmann, Lars O.; Haake, Hendrik; Muellenbach, Ralf M.; Bals, Robert; Kredel, Markus; Langer, Frank; Wilkens, Heinrike; Trudzinski, Franziska C.
ASAIO Journal 64 (4), July/August 2018: e64 – e67.

Die Behandlung eines ungewöhnlichen kardiogenen Schocks.
H. Haake, K. Grün-Himmelmann, U. Kania, F. Trudzinski, P. M. Lepper & J. vom Dahl.
Medizinische Klinik – Intensivmedizin und Notfallmedizin volume 113, 2018: 131–134.

The Homburg Lung: Efficacy and Safety of a Minimal-Invasive Pump-Driven Device for Veno-Venous Extracorporeal Carbon Dioxide Removal.
Seiler, Frederik; Trudzinski, Franziska C.; Hennemann, Kai; Niermeyer, Tom; Schmoll, Christian; Kamp, Annegret; Bals, Robert; Muellenbach, Ralf M.; Haake, Hendrik; Lepper, Philipp M.
ASAIO Journal 63 (5), September/October 2017: 659-665.

Pentaglobin treatment of pcr-positive parvo B19 myocarditis.
Bernhard Maisch, Hendrik Haake, Nadine Schlotmann, Reinhard C. Funck, Sabine Pankuweit.
Journal of the American College of Cardiology, Volume 67, Issue 13, 5 April 2016: 1348.

Outcome of patients with Interstitial Lung Disease Treated with Extracorporeal Membrane Oxygenation for Acute Respiratory Failure.
Franziska C. Trudzinski, Franziska Kaestner,  Hans-Joachim Schäfers, Sebastian Fähndrich, Frederik Seiler, Philip Böhmer, Oliver Linn, Ralf Kaiser, Hendrik Haake, Frank Langer, Robert Bals, Heinrike Wilkens and Philipp M. Lepper. 
Am J Respir Crit Care Med, 2016 Mar 1; 193 (5): 527-33.

AFFECT: a prospective, open-label, multicenter trial to evaluate the feasibility and safety of a short-term treatment with subcutaneous certoparin in patients with persistent non-valvular atrial fibrillation.
Tebbe, U., Oeckinghaus, R., Appel, KF., Haake, H. et al.
Clin Res Cardiol 97, 2008: 389–396.

Noninvasive ventilation in covid-19 patients aged ≥ 70 years  – a prospective multicentre cohort study.
Kamil Polok, Jakub Fronczek, Antonio Artigas, Hans Flaatten, Bertrand Guidet, Dylan W. De Lange, Jesper Fjølner, Susannah Leaver, Michael Beil, Sigal Sviri, Raphael Romano Bruno, Bernhard Wernly, Bernardo Bollen Pinto, Joerg C. Schefold, Dorota Studzińska, Michael Joannidis, Sandra Oeyen, Brian Marsh, Finn H. Andersen, Rui Moreno, Maurizio Cecconi, Christian Jung, Wojciech Szczeklik on behalf of COVIP Study Group.
Critical Care volume 26, 2022, Article number: 224.

The association of the Activities of Daily Living and the outcome of old intensive care patients suffering from COVID-19.
Bruno RR, Wernly B, Flaatten H, Fjølner J, Artigas A, Baldia PH, Binneboessel S, Bollen Pinto B, Schefold JC, Wolff G, Kelm M, Beil M, Sviri S, van Heerden PV, Szczeklik W, Elhadi M, Joannidis M, Oeyen S, Kondili E, Marsh B, Wollborn J, Andersen FH, Moreno R, Leaver S, Boumendil A, De Lange DW, Guidet B, Jung C; COVIP study group. 
Ann Intensive Care. 2022 Mar 18; 12 (1): 26.

The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study.
Jung C, Flaatten H, Fjølner J, Bruno RR, Wernly B, Artigas A, Bollen Pinto B, Schefold JC, Wolff G, Kelm M, Beil M, Sviri S, van Heerden PV, Szczeklik W, Czuczwar M, Elhadi M, Joannidis M, Oeyen S, Zafeiridis T, Marsh B, Andersen FH, Moreno R, Cecconi M, Leaver S, Boumendil A, De Lange DW, Guidet B; COVIP study group. 
Crit Care. 2021 Apr 19; 25(1): 149.

Extracorporeal life support in COVID-19-related acute respiratory distress syndrome: A EuroELSO international survey. 
Mang S, Kalenka A, Broman LM, Supady A, Swol J, Danziger G, Becker A, Hörsch SI, Mertke T, Kaiser R, Bracht H, Zotzmann V, Seiler F, Bals R, Taccone FS, Moerer O, Lorusso R, Bělohlávek J, Muellenbach RM, Lepper PM; COVEC-Study Group.
Artif Organs. 2021 May; 45 (5): 495-505.

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes.
Lars Wallentin, Richard C. Becker, Andrzej Budaj, Christopher P. Cannon, Håkan Emanuelsson, Claes Held, Jay Horrow, Steen Husted, Stefan James, Hugo Katus, Kenneth W. Mahaffey, Benjamin M. Scirica, Allan Skene, Philippe Gabriel Steg, Robert F. Storey and Robert A. Harrington, for the PLATO Investigators.
N Engl J Med 2009; 361: 1045-1057.

Rivaroxaban for Thromboprophylaxis in Acutely Ill Medical Patients.
Alexander T. Cohen,  Theodore E. Spiro, Harry R. Büller, Lloyd Haskell, Dayi Hu, Russell Hull, Alexandre Mebazaa,  Geno Merli, Sebastian Schellong, Alex C. Spyropoulos and Victor Tapson, for the MAGELLAN Investigators.
N Engl J Med 2013; 368: 513-523.

Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation.
Manesh R. Patel, Kenneth W. Mahaffey, Jyotsna Garg, Guohua Pan, Daniel E. Singer,  Werner Hacke, Günter Breithardt, Jonathan L. Halperin, Graeme J. Hankey, Jonathan P. Piccini, Richard C. Becker, Christopher C. Nessel, John F. Paolini, Scott D. Berkowitz, Keith A.A. Fox, Robert M. Califf and the ROCKET AF Steering Committee, for the ROCKET AF Investigators.
N Engl J Med 2011; 365: 883-891

Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes.
Gheorghiade M, Greene SJ, Filippatos G, Erdmann E, Ferrari R, Levy PD, Maggioni A, Nowack C, Mebazaa A; COMPOSE Investigators and Coordinators.
Eur J Heart Fail. 2012 Sep;14 (9): 1056-66.

Anticoagulation With Otamixaban and Ischemic Events in Non–ST-Segment Elevation Acute Coronary Syndromes. The TAO Randomized Clinical Trial.
Philippe Gabriel Steg, Shamir R. Mehta, Charles V. Pollack Jr, et.al.
JAMA. 2013;310(11): 1145-1155.

Rivaroxaban vs. vitamin K antagonists for cardioversion in atrial fibrillation.
Cappato R, Ezekowitz MD, Klein AL, Camm AJ, Ma CS, Le Heuzey JY, Talajic M, Scanavacca M, Vardas PE, Kirchhof P, Hemmrich M, Lanius V, Meng IL, Wildgoose P, van Eickels M, Hohnloser SH; X-VeRT Investigators. Eur Heart J. 2014 Dec 14;35(47): 3346-55.

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure.
John J.V. McMurray, Milton Packer, Akshay S. Desai, Jianjian Gong, Martin P. Lefkowitz, Adel R. Rizkala, Jean L. Rouleau, Victor C. Shi,  Scott D. Solomon, Karl Swedberg and Michael R. Zile for the PARADIGM-HF Investigators and Committees.
N Engl J Med 2014; 371: 993-1004.

Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.
Marc P. Bonaca, Deepak L. Bhatt, Marc Cohen, Philippe Gabriel Steg, Robert F. Storey, Eva C. Jensen, Giulia Magnani,  Sameer Bansilal,  M. Polly Fish, Kyungah, Olof Bengtsson, Ton Oude Ophuis, Andrzej Budaj, Pierre Theroux, Mikhail Ruda, Christian Hamm,  Shinya Goto, Jindrich Spinar, José Carlos Nicolau, Robert G. Kiss, Sabina A. Murphy, Stephen D. Wiviott, Peter Held, Eugene Braunwald and Marc S. Sabatine for the PEGASUS-TIMI 54 Steering Committee and Investigators.
N Engl J Med 2015; 372: 1791-1800.

Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial.
Pascal Vranckx,  Marco Valgimigli, Peter Jüni, Christian Hamm, Philippe Gabriel Steg, on behalf of the GLOBAL LEADERS Investigators.
The Lancet, VOLUME 392, ISSUE 10151, SEPTEMBER 15, 2018: 940-949.

Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.
Paul W. Armstrong, Burkert Pieske, Kevin J. Anstrom, Justin Ezekowitz, Adrian F. Hernandez,  Javed Butler, Carolyn S.P. Lam, Piotr Ponikowski, Adriaan A. Voors, Gang Jia, Steven E. McNulty, Mahesh J. Patel,  Lothar Roessig,  Joerg Koglin and Christopher M. O’Connor, for the VICTORIA Study Group.
N Engl J Med 2020; 382: 1883-1893.

Dual Vasopressin Receptor Antagonism to Improve Congestion in Patients With Acute Heart Failure: Design of the AVANTI Trial.
Goldsmith SR, Burkhoff D, Gustafsson F, Voors A, Zannad F, Kolkhof P, Staedtler G, Colorado P, Dinh W, Udelson JE. et al.
J Card Fail. 2021 Feb; 27 (2): 233-241.

Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation.
Steffen Desch, Anne Freund, Ibrahim Akin, Michael Behnes,  Michael R. Preusch, Thomas A. Zelniker, Carsten Skurk, Ulf Landmesser, Tobias Graf, Ingo Eitel, Georg Fuernau, Hendrik Haake and Holger Thiele et al., for the TOMAHAWK Investigators.
N Engl J Med December 30, 2021; 385: 2544-2553.